Cyrene may refer to:

• Cyrene (mythology), a Greek mythological figure
• Cyrene, Libya, an ancient Greek colony in North Africa
• The USS Cyrene (AGP-13), a motor torpedo boat tender
• 133 Cyrene, an asteroid
• Cyrene (Xena), a fictional character in the Xena TV series

See also

• Cyrenaica, the region around Cyrene

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